Other works of this and other research groups focus on constructing mathematical models using data from mouse tumor experiments, which include xenografted neuroendocrine tumor model treated by α-emitting 212Pb-DOTAMTATE (21), thyroid cancer xenograft model treated by α-emitting 212At which naturally accumulates in thyroid (22), and transgenic murine model of metastatic breast cancer treated by α-emitters 225Ac and 213Bi, conjugated with anti-HER2/neu antibodies (23). Here, ERBB2 is linked to neuroendocrine neoplasm.