Certain studies have identified a correlation,[28,29] whereas others have not observed any association.[30,31] However, our study supports the connection between genetically predicted CCL11 levels and CHD, and its possible mechanism is that elevated CCL11 may exacerbate atherosclerotic plaque development by recruiting eosinophils and other immune cells, thus intensifying vascular inflammation and plaque instability. Here, CCL11 is linked to coronary artery disorder.