SMARCA4-deficient non-small cell lung cancer: Infiltrative poorly differentiated adenocarcinoma of the right lung with EGFR exon 21 L858R mutation, classified as stage IVB (cT3N2M1c) involving the right parietal lobe, right clavicle, and right sacroiliac joint. The gene discussed is SMARCA4; the disease is non-small cell lung carcinoma.