As for the mediation of X-24344 levels in the causal relationship between CD3 on CD39+ activated Treg and prostatitis and that of histidine betaine (hercynine) levels and proline-to-glutamate ratio in the causal relationship between CD14–CD16+ monocytes and prostatitis, no similar theories were reported in the available articles. This evidence concerns the gene ENTPD1 and male reproductive organ cancer.