CD3 on CD39+ activated Treg influenced the risk of prostatitis via the X-24344 levels; the absolute count of CD14– CD16+ monocytes affected the risk of prostatitis via the histidine betaine (hercynine) levels and the proline-to-glutamate ratio; and HLA-DR+ CD4+ %T cells affected the prostatitis risk via the glutamine degradant levels. This evidence concerns the gene ENTPD1 and male reproductive organ cancer.