The half-lives of protein C and antithrombin III are 58 and 8 hours, respectively, so SPG episodes are usually observed for at least 2 days after shock and DIC in sepsis patients, and this is called “delayed”.[31] In our study, it was concluded that SPG occurred 2.60 ± 1.70 days after shock (median), consistent with the “delayed” of SPG. The gene discussed is SERPINC1; the disease is Sepsis.