ACSL4 and posterior cortical atrophy: Additionally, in animal studies, Wang et al found that induced ferroptosis in vivo could inhibit PCa tumor growth and metastasis, improving mouse survival rates.[12] Modulating ACSL4 levels could promote docetaxel resistance in PCa.[21] These findings collectively indicated that ACSL4 plays an important role in the progression, treatment, and prognosis of PCa.