Relevant literature showed that quercetin can significantly decrease the expression levels of IL-4, IL-5, IL-6, IgE in peripheral blood and NLRP3, ASC, and caspase-1 proteins in lung tissue of rats, reducing airway inflammation and alleviating asthma symptoms.[14–17] Epithelial-to-mesenchymal plays a vital role in the progression of airway remodeling. The gene discussed is IGHE; the disease is asthma.