CRP and brain infarction: The abnormal physiological concentration of serum inflammatory factors can induce PSF by disrupting metabolism and interfering with the synthesis and release of neurotransmitters.[30] Relevant studies have shown significant differences in serum CRP and Hcy levels between patients with PSF and those with NPSF.[14,31] Wang et al[32] found that elevated serum CRP and Hcy levels were risk factors of PSF in elderly patients with cerebral infarction, which was consistent with the results of this study.