In the remaining two RCT measuring CRP, no significant difference between treatment groups was found following average weekly doses (mean ± sd) of 2133 μg ± 400 in Latino and African American adults with pre-diabetes and hypovitaminosis D(24) or monthly doses of 3000 μg or 300 μg in Asian Indian obese children and adolescents(25). Here, CRP is linked to diabetes mellitus.