APOA1 and atherosclerosis: Lastly, although both apo(B) and Lp(a) promote lipid deposition through LDL, the distinctive structure of apo(a) makes Lp(a) more dangerous in terms of plaque rupture and thrombosis, as the structural similarity between apo(a) and plasminogen can inhibit fibrinolysis, influencing the risk of ASCVD [47].