PPARA and cardiac hypertrophy: Ginsenoside Rb1, a dammarane-type triterpene saponin compound mainly distributed in Panax ginseng (Ren shen), has been demonstrated to ameliorate the aberrant expression of cardiac energy metabolism-related enzymes and promote cardiac FAO by inhibiting the Fas-associated death domain and activating the peroxisome proliferator-activated receptor alpha (PPARα) signaling pathway, which ultimately attenuates cardiac hypertrophy and cardiac fibrosis [57].