PCNA and primary ovarian failure: In addition, the ROS and BCL2 levels in the ovaries of the treatment group were significantly decreased, and the SOD, PCNA, MVH, and BAX levels were significantly increased, indicating that the oxidative stress and apoptosis of cells in the ovaries were effectively inhibited and that ovarian function was significantly restored, suggesting the potential of PCs as drugs for the treatment of premature ovarian failure caused by oxidative stress.