It has also been reported that MTHFR C677T could affect LDL-C levels (Yilmaz et al., 2003; Pitsavos et al., 2006), and our findings indicate an association of MTHFR C677T and A1298C polymorphisms with FBG levels in patients with T2DM in the Dali area, Yunnan Province. Here, MTHFR is linked to type 2 diabetes mellitus.