We examined the subtype-specific-marker genes and identified that the markers of cancer stemness feature including the TNFAIP3 and KDM5B were also expressed in the B cell 1 and the markers of plasma cells were expressed in the B cells 3 (Fig. 2G), suggesting that the B cells 1may be the stemness B cells and the B cells 3 may be the mature plasma B cells. This evidence concerns the gene KDM5B and cancer.