Interestingly, transcriptomic analysis of CD34+ cells from the BM of αPD-1-treated individuals with HL revealed 612 DEGs (Supplementary Table 3), of which 202 were upregulated and 410 were downregulated (p-value < 0.05) compared to CD34+ cells from samples from HL patients isolated at diagnosis. This evidence concerns the gene CD34 and Hodgkins lymphoma.