Only a 10-year-old female patient from family 3 was observed to be positive for anti-endomysial Ab (AEA), anti-TPO antibodies (363.4 IU/ml), anti-Tissue Transglutaminase IgG (15.2 IU/ml), and anti-Tissue Transglutaminase (IgA >200 IU/ml) tests indicating the presence of Hashimoto thyroiditis and Celiac Disease. The gene discussed is TGM2; the disease is Hashimoto thyroiditis.