The miRNA-gene expression analysis of the key DE miRNAs predicted 10 hub genes, namely PTEN, MYC, AGO1, HASPA1B, BCL2, EEEF1A1, AKT1, CPEB4, FASN, and PRPF8, that are significantly deregulated in T1D individuals (FDR p-value ≤0.05) (Figure 3A). Here, PRPF8 is linked to type 1 diabetes mellitus.