PTEN and type 1 diabetes mellitus: In conclusion, our study highlights the prospective role of hsa-miR-320a-3p in the pathophysiology of T1D by presenting known evidences for dysregulated expression of miRNA target-transcription factor network involving PTEN, AKT1, BCL2, FOXO1 and MYC. The correlations of hsa-miR-320a-3p with additional interacting partners indicate its wide potential in insulin signaling and metabolic pathways characterizing the development of T1D.