Secondly, in terms of single organ metastasis, EGFR mutation was associated with lung, brain, and bone metastasis of NSCLC, KRAS mutation was associated with lung and brain metastasis of NSCLC, and ROS1 mutation was associated with lung and pleural metastasis of NSCLC, but the total metastasis rate was not different compared with wild type. Here, EGFR is linked to non-small cell lung carcinoma.