Exosomal miRNAs were found to affect cancer in two ways, which is the regulation of expression of protein-encoded oncogenes and tumour suppressors, such as anaplastic lymphoma kinase, tumour protein p53, vascular endothelial growth factor (VEGF) family, calcineurin-E; or as oncogenes and tumour suppressors such as let-7, miR-21, and miR-34 families (113). The gene discussed is ALK; the disease is neoplasm.