Studies done by Fraser (2016) discovered that leucine-rich repeat kinase 2 (LRRK2) is a biomarker in Parkinson Disease patients’ urine exosomes that indicates the likelihood that those who carry the LRRK2 mutation will develop the disease and that α-synuclein aggregation could be a significant factor in Parkinson’s disease pathogenesis (10). The gene discussed is LRRK2; the disease is Parkinson disease.