Additionally, the HLA-B*15:02 allele is known for its association with carbamazepine and phenytoin-induced SJS/TEN, particularly in Southeast Asian populations (Ferrell and McLeod, 2008; Chang et al., 2011; Wei et al., 2012; Ahmed et al., 2021), while the HLA-B*15:13 allele is associated with phenytoin-induced SCARs in the Malay population (Chang et al., 2017). The gene discussed is HLA-B; the disease is toxic epidermal necrolysis.