SLC6A4 and anxiety disorder: It has beenhypothesized that children with African American and Caucasian ancestors representsimilar manifestations of anxiety disorder, however, the outcomes of treatment weredifferent because of treatment barriers [64].Genetic variations, especially in genes encoding enzymes and receptors related toserotonin, including bi- and triallelic SLC6A4 5-HTTLPR may contribute to theetiology of SAD and even affect how it responds to treatment [65].