For instance, while Miller et al. 17 reported no significant differences in the expression of catabolic markers between patients with HF compared to CON, while Forman et al. 23 found elevated expression of atrophy-promoting genes (such as forkhead box proteins O1 and O3 and ubiquitin B), some of which were associated with VO2peak. The gene discussed is FOXO1; the disease is hydrops fetalis.