CRP and myelodysplastic syndrome: Patients with the UBA1 p.Met41Val mutation were more likely to experience chondritis (14.3%), higher CRP levels, and more frequent myelodysplastic syndrome (MDS) (68.6%) and had a decreased survival rate.2 Interestingly, the UBA1 p.Met41Leu mutation was more common in patients with mild-to-moderate disease (29.6%) as were the non-Met-41 variants.10 This can also be observed in our patient, who has the p.Met41Leu mutation, which may predict that his disease will have a indolent course compared to the other more aggressive forms of this condition.