The p-values of both ER and PR status were less than 0.05, which indicates a significant association between these markers and the tumor grade, with Cramér's V of approximately 0.4 for both suggesting moderate association, and OR of 0.126 for ER and 0.167 for PR indicating that it is more likely for the L. group to be ER/PR+ and for the H. group to be ER/PR-. This evidence concerns the gene ESR1 and neoplasm.