Surprisingly, the expression of Kcr is downregulated in liver, stomach, and kidney cancer, while in thyroid, oesophagus, colon, pancreas, and lung cancer, an upregulation of Kcr levels has been found.[53] The different effects are thought to be a result of the regulation of different key cancer‐related proteins via histone and non‐histone crotonylation in different cancer types. The gene discussed is CLEC4F; the disease is cancer.