CD5 and graft versus host disease: The results demonstrated that 12 C CAR-NK cells exerted cytotoxic ability against both auto-T cells and allogeneic normal T cells compared to NT-NK cells (Fig. 4b), which facilitated manufacturing “off-the-shelf” universal CD5 CAR-NK cell products with extremely diminished risk of GVHD even though a side effect towards normal T cells.