A 35-year-old male (ID 9039) with clinical signs of RP was found to carry a known likely pathogenic c.658C > T; p.(Arg220Trp) missense variant in the PRPH2 gene and a likely pathogenic c.854C > G; p.(Pro285Arg) missense variant in the RHO gene. Here, PRPH2 is linked to retinitis pigmentosa 1.