KDM4A and urinary bladder carcinoma: By analyzing the BLCA_TCGA database, the results suggested that the expression level of KDM4A in bladder cancer was significantly higher than that in normal bladder epithelial tissues (p < 0.001), and patients with higher expression of KDM4A generally had a poor disease-free survival time compared with those with lower KDM4A expression, although the difference was not statistically significant (p = 0.28) (Fig. 8A).