The log-transformed concentrations for suPAR (odds ratio [OR] = 8.4, 95% CI: 2.7–29.4, p < 0.005), sTREM (OR = 2.6, 95% CI: 1.5–5.0, p < 0.005), and IL-1Ra (OR = 2.4 [1.4–4.4, p < 0.005]) were significant univariable regressors of D28 mortality, along with lymphocyte count, age > 65, ALI or ARDS, chronic cardiac disease rate, and c-reactive protein (Supplementary Table S2). The gene discussed is CRP; the disease is acute respiratory distress syndrome.