It is known that the N-terminal domain of HSV-1 UL24 (1-192 AA) drives the redistribution of nucleolin and B23, and is important for the pathogenesis of HSV-1 ocular infection [36,37,48,57], while the C-terminal domain of HSV-1 UL24 (190-269 AA) is necessary and sufficient for targeting the Golgi apparatus and influencing the syncytial plaque phenotype [48,58]. The gene discussed is NUCLEOLIN; the disease is eye infection.