Furthermore, Xie et al. [76] observed that after booster immunization with quadrivalent inactivated influenza vaccine (QIV), mice carrying the IFITM3 rs12252-C/C genotype with an N-terminal truncation of 21 amino acids (NΔ21) exhibited higher levels of HI, MN, and IgG antibodies against influenza viruses compared to WT mice. The gene discussed is IFITM3; the disease is influenza.