In this study, we explore IL17 (A7448G and G197A) and toll-like receptor TLR4 (Asp299Gly and Thr399Ile) gene polymorphisms in patients with simple steatosis (MAFL) or steatohepatitis (MASH) and MASLD. The gene discussed is TLR4; the disease is metabolic dysfunction-associated steatohepatitis.