Serum levels of TLR4 were distributed significantly differently between MASLD patients and controls (Mann–Whitney U test, p < 0.0001), with patients with MASLD having higher values of IL17 compared to controls (median = 1820.5, IQR: 1482.4–1963.7 vs. median = 1296.6, IQR: 983.4–1460.6). The gene discussed is TLR4; the disease is metabolic dysfunction-associated steatotic liver disease.