This study showed that there were strong associations between PE and the polymorphisms methylenetetrahydrofolate reductase (MTHFR) C677T, PAI-1 4G/5G, and ITGB3 (Glanzmann thrombasthenia), suggesting PE is a different phenotype in VTE genetic studies [18]. Here, MTHFR is linked to Glanzmann thrombasthenia 1.