TA:Prevents behavioral impairments, such as hyperactivity, decreased object recognition, and defective spatial reference memory. reduces brain parenchymal and cerebral vascular amyloid deposits, and mitigates neuroinflammation.Decreases the production of various Aβ species, including oligomers. These effects were linked to the inhibition of BACE1 expression and activity, and a shift towards non-amyloidogenic APP processing pathways, suggesting that TA might serve as a potential prophylactic treatment for AD. The gene discussed is BACE1; the disease is Alzheimer disease.