It has been demonstrated that treatment with lyophilized extracts of atemoya seeds, peel, and pulp has a nephroprotective effect due to its antioxidant and anti-inflammatory potential, as evidenced by increased levels of all antioxidant enzymes and reduced plasma levels of IL-6 and TNF-α, which are cytokines that rise when renal alterations occur, being involved in several diseases of this organ (acute kidney disease, chronic kidney disease, glomerulonephritis, focal segmental glomerulosclerosis) [14]. This evidence concerns the gene TNF and chronic kidney disease.