On the intersection, 39 targets (APH1A, BCL2L1, CA12, CTSD, FAAH, FDPS, HIF1A, HMGCR, HPRT1, HSD17B10, HSP90AA1, JAK3, KMT5A, MAPK1, MMP3, MSR1, PNP, PTGS1, PTPN1, SQLE, SYK, TDP1, TYMP, TYMS, VDR, VEGFA, CDC25C, KIF20B, MMP13, PDE4D, ALOX5AP, CDK5R1, MGAM, PTAFR, BLM, HPSE, IGF2R, INSR, and JAK1) were identified, which indicates that these common genes of OSCC and BC could respond to any of the 147 phytochemical candidates. The gene discussed is PTAFR; the disease is breast cancer.