Based on data integration, 39 proteins (APH1A, BCL2L1, CA12, CTSD, FAAH, FDPS, HIF1A, HMGCR, HPRT1, HSD17B10, HSP90AA1, JAK3, KMT5A, MAPK1, MMP3, MSR1, PNP, PTGS1, PTPN1, SQLE, SYK, TDP1, TYMP, TYMS, VDR, VEGFA, CDC25C, KIF20B, MMP13, PDE4D, ALOX5AP, CDK5R1, MGAM, PTAFR, BLM, HPSE, IGF2R, INSR, and JAK1) were identified and assessed for their role in cancer metastasis. Here, TDP1 is linked to cancer.