CLDN4 and cancer: -Claudin-4 overexpression in ovarian cancer drives paclitaxel resistance-Claudin-4 expressing cells exhibited a higher response to paclitaxel, but no cisplatin, after cotreatment with CMP or shCLDN4-Cancer cells lacking claudin-4 are characterized by inhibition of G2-M progression of cell cycle and abundant of mitotic figures-Claudin-4 regulates the polymerization of microtubules, which may be a potential paclitaxel-resistance mechanism