On the other hand, another research group found that the reduction in CD36, a membrane glycoprotein that contributes to metabolic disorders such as obesity, was correlated with a decrease in mitochondrial ATP generation and P2X7 expression, suggesting that the suppression of CD36 attenuates adipogenesis via P2X7R [102]. The gene discussed is CD36; the disease is obesity due to melanocortin 4 receptor deficiency.