TACSTD2 and neoplasm: The AlphaFold 3 model has significantly enhanced the precision of joint structure prediction for complexes, including proteins, nucleic acids, small molecules, ions, and modified residues [54] given the similar binding modes of N14 and N152 and considering that N14 surpasses N152 in mediating receptor internalization as well as inhibiting the proliferation and migration of Trop2-positive tumor cells.