Although several studies have shown that plant-based materials may be useful for the treatment and prevention of Alzheimer’s disease (AD) by inhibiting butyrylcholinesterase (BChE) and acetylcholinesterase (AChE), however, the effect of enzymatic hydrolysis of chia protein on AD has not been reported [33]. The gene discussed is BCHE; the disease is early-onset autosomal dominant Alzheimer disease.