Although several studies have shown that plant-based materials may be useful for the treatment and prevention of Alzheimer’s disease (AD) by inhibiting butyrylcholinesterase (BChE) and acetylcholinesterase (AChE), however, the effect of enzymatic hydrolysis of chia protein on AD has not been reported [33]. This evidence concerns the gene ACHE and early-onset autosomal dominant Alzheimer disease.