Genomics has also given extensive information about the genes associated with AD, such as apolipoprotein E (APOE), BIN1, ABCA7, PICALM, MS4A4E/MS4A6A, CD2AP, CD33, EPHA1, CLU, CR1, and SORL1 all being associated with late-onset AD (LOAD) [82,83,84,85]. Here, APOE is linked to Alzheimer disease.