CREBBP and Chiari malformation type I: Reported mutations in patients with Rubinstein–Taybi and CM1 have included CREBBP, c.3546ins, c.3546insCC, p.R2004X, c.4482dupC, c.4944dupC, and a 520.7 kb microdeletion on 16p13.3 (encompassing CREBBP) [37,104,105,106,107].