A comparative double-blind clinical trial by Rahimzadeh demonstrated that adding growth hormone to platelet-rich plasma for intra-articular injection improved the function of the osteoarthritic knee joint in a short period of time, with no observed complications, indicating the beneficial effect of the combination of growth hormone and platelet-rich plasma for individuals with knee osteoarthritis [9]. The gene discussed is GH1; the disease is osteoarthritis, knee.