Number of proteins such as CD97 (ADGRE5), adhesion G protein-coupled receptor E2 (AGRE2), antileukoproteinase (SLPI), protein S100-A8 (S100-A8), protein S100-A9 (S100-A9), caspase recruitment domain-containing protein 14 (CARD14) are involved in inflammatory and cancer process. The gene discussed is S100A8; the disease is cancer.