To date, there are eight known genes that are causative of OCA with autosomal recessive inheritance: TYR (OCAIA and OCAIB), OCA2 (OCAII and Albinism, brown oculocutaneous), TYRP1 (OCAIII), SLC45A2 (OCAIV), OCA5 (OCAV), SLC24A5 (OCAVI and variations in skin pigmentation), LRMDA (OCAVII), and DCT (OCAVIII). The gene discussed is TYR; the disease is oculocutaneous albinism.