In a recent study, the eicosanoid and pro-resolutive parameters of patients with COVID-19 with severe symptoms, such as ARDS, were compared to the lipid profiles of only moderately affected patients, the results showing that the lipid mediator products of ALOX12 and COX2 decreased, while those of ALOX5 and cytochrome P450 increased [27]. Here, ALOX12 is linked to acute respiratory distress syndrome.