It had been reported that TIGIT expression retained the capacity of proliferation of CD8+ T cells with higher levels of Ki67 expression and an increased proliferation index in the carboxyfluorescein-diacetate succinimidyl ester (CFSE) assay compared with TIGIT− CD8+ T cells of newly diagnosed AML patients [40]. This evidence concerns the gene MKI67 and acute myeloid leukemia.