However, in the hippocampus of HCC mice, the expression of inflammatory cytokines and clock genes was increased, and the number of proliferating cells in the neurogenic niche was decreased, while the IR for c-Fos, pERK, GFAP, IBA, and 8-OHdG was not affected [36,37]. This evidence concerns the gene GFAP and hepatocellular carcinoma.