BAX and breast carcinoma: UA also modulated the expression of apoptosis-related genes of the apoptosis pathway in SKBR-3 breast cancer cells with significant elevation of mRNA for caspases 3, 4, 10, TRAF 5 and 6, numerous TNF family members, APAF1, Bik, Bak1, Bax, Bok, MCL1, p53, Chek1, Chek2, DAPK2, RIPK2, GADD45A and reduction in mRNA for Bcl2, Bcl2L11, Bag1, Bag4.