For example, in the case of hsa-miR-874-3p, in our study, this miRNA is upregulated; in the study by Suento et al., hsa-miR-874-3p can be used as a therapeutic target in major depressive disorder in view of the fact that miR-874-3p may play a major role in the prevention of lipopolysaccharide-induced depressive behavior through inhibition of indoleamine 2,3-dioxygenase 1 expression [32]. Here, IDO1 is linked to major depressive disorder.