A virus-mediated FIG4-rescuing therapy that significantly prolongs survival and restores motor performance in animal models of FIG4 mutations paves the way for the discovery of an effective treatment for this type of genetic parkinsonism [34] As presymptomatic diagnosis via genetic tools is necessary for the timely application of disease-modifying treatments, it is important that clinicians and geneticists become aware of novel genetic types of PD or other parkinsonian syndromes. This evidence concerns the gene FIG4 and Parkinson disease.